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1

Inhibition of HSP70 and a Collagen-Specific Molecular Chaperone (HSP47) Expression in Rat Osteoblasts by Microgravity

YASUHIRO KUMEI, SADAO MORITA, HITOYATA SHIMOKAWA, KEI'ICHI OHYA, HIDEO AKIYAMA, MASAHIKO HIRANO, CLARENCE F. SAMS, PEGGY A. WHITSON

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 10.77 MB

2003

2

Calcium-binding properties of fetuin in fetal bovine serum

Michiko Suzuki, Hitoyata Shimokawa, Yuzo Takagi, Satoshi Sasaki

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1994

Language:

english

File:

PDF, 824 KB

english, 1994

3

Enhanced ectopic bone formation using a combination of plasmid DNA impregnation into 3-D scaffold and bioreactor perfusion culture

Hossein Hosseinkhani, Masaya Yamamoto, Yasuyuki Inatsugu, Yosuke Hiraoka, Sachiko Inoue, Hitoyata Shimokawa, Yasuhiko Tabata

Journal:

Year:

2006

Language:

english

File:

PDF, 630 KB

english, 2006

4

Effects of neurectomy and tenotomy on the bone mineral density and strength of tibiae

Hiroshi Nakamura, Sadao Morita, Yasuhiro Kumei, Kazuhiro Aoki, Hitoyata Shimokawa, Keiichi Ohya, Ken-ichi Shinomiya

Journal:

Acta Astronautica

Year:

2001

Language:

english

File:

PDF, 464 KB

english, 2001

5

Enamel proteins and extracellular matrix molecules are co -localized in the pseudocystic stromal space of adenomatoid odontogenic tumor

Masashi Murata, Jun Cheng, Kazuhito Horino, Kohji Hara, Hitoyata Shimokawa, Takashi Saku

Journal:

Journal of Oral Pathology & Medicine

Year:

2000

Language:

english

File:

PDF, 384 KB

english, 2000

6

Disturbed tooth eruption in osteopetrotic (op/op) mice: histopathogenesis of tooth malformation and odontomas

Hiroko Ida-Yonemochi, Tadashi Noda, Hitoyata Shimokawa, Takashi Saku

Journal:

Journal of Oral Pathology & Medicine

Year:

2002

Language:

english

File:

PDF, 4.21 MB

english, 2002

7

Detection of collagenase mRNA in odontoclasts of bovine root-resorbing tissue byIn situhybridization

Takeshi Okamura, Hitoyata Shimokawa, Yuzo Takagi, Hiroshi Ono, Satoshi Sasaki

Journal:

Calcified Tissue International

Year:

1993

Language:

english

File:

PDF, 2.58 MB

english, 1993

8

Immobilized DPP and other proteins modify OCP formation

Yutaka Doi, Takashi Horiguchi, Seung-Hyo Kim, Yutaka Moriwaki, Nobukazu Wakamatsu, Masanori Adachi, Hiroshi Shigeta, Satoshi Sasaki, Hitoyata Shimokawa

Journal:

Calcified Tissue International

Year:

1993

Language:

english

File:

PDF, 1.79 MB

english, 1993

9

Detection of collagen degradation products in bone

Yoshinori Kuboki, Hitoyata Shimokawa, Toshio Ono, Satoshi Sasaki

Journal:

Calcified Tissue International

Year:

1973

Language:

english

File:

PDF, 682 KB

english, 1973

10

Purification, characterization, and biosynthesis of bovine enamelins

Yorimasa Ogata, Hitoyata Shimokawa, Satoshi Sasaki

Journal:

Calcified Tissue International

Year:

1988

Language:

english

File:

PDF, 2.31 MB

english, 1988

11

Immunohistochemical localization of α2HS glycoprotein in dentinHS glycoprotein in dentin

Yuzo Takagi, Hitoyata Shimokawa, Michiko Suzuki, Hiroaki Nagai, Satoshi Sasoki

Journal:

Calcified Tissue International

Year:

1990

Language:

english

File:

PDF, 3.22 MB

english, 1990

12

Expression of dentin matrix protein 1 (DMP1) in nonmineralized tissues

Makiko Terasawa, Reiko Shimokawa, Tatsuo Terashima, Keiichi Ohya, Yuzo Takagi, Hitoyata Shimokawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

2004

Language:

english

File:

PDF, 455 KB

english, 2004

13

Effects of mechanical strain on proliferation and differentiation of bone marrow stromal cell line ST2

Mariko Koike, Hitoyata Shimokawa, Zuisei Kanno, Keiichi Ohya, Kunimichi Soma

Journal:

Journal of Bone and Mineral Metabolism

Year:

2005

Language:

english

File:

PDF, 320 KB

english, 2005

14

Bovine deciduous dentine is more susceptible to osteoclastic resorption than permanent dentine: results of quantitative analyses

Bobby John Varghese, Kazuhiro Aoki, Hitoyata Shimokawa, Keiichi Ohya, Yuzo Takagi

Journal:

Journal of Bone and Mineral Metabolism

Year:

2006

Language:

english

File:

PDF, 638 KB

english, 2006

15

Expression of MT1-MMP during deciduous tooth resorption in odontoclasts

Busayarat Linsuwanont-Santiwong, Yuzo Takagi, Keiichi Ohya, Hitoyata Shimokawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

2006

Language:

english

File:

PDF, 443 KB

english, 2006

16

Lipopolysaccharide-induced bone resorption is increased in TNF type 2 receptor-deficient mice in vivo

Anower Hussain Mian, Hiroaki Saito, Neil Alles, Hitoyata Shimokawa, Kazuhiro Aoki, Keiichi Ohya

Journal:

Journal of Bone and Mineral Metabolism

Year:

2008

Language:

english

File:

PDF, 712 KB

english, 2008

17

Inhibition of the classical NF-κB pathway prevents osteoclast bone-resorbing activity

Niroshani S. Soysa, Neil Alles, Hitoyata Shimokawa, Eijiro Jimi, Kazuhiro Aoki, Keiichi Ohya

Journal:

Journal of Bone and Mineral Metabolism

Year:

2009

Language:

english

File:

PDF, 456 KB

english, 2009

18

Bovine dentine organic matrix down-regulates osteoclast activity

Wantida Sriarj, Kazuhiro Aoki, Keiichi Ohya, Yuzo Takagi, Hitoyata Shimokawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

2009

Language:

english

File:

PDF, 366 KB

english, 2009

19

The tumor necrosis factor type 2 receptor plays a protective role in tumor necrosis factor-α-induced bone resorption lacunae on mouse calvariae

Kenichi Nagano, Neil Alles, Anower Hussain Mian, Asako Shimoda, Nobuyuki Morimoto, Yukihiko Tamura, Hitoyata Shimokawa, Kazunari Akiyoshi, Keiichi Ohya, Kazuhiro Aoki

Journal:

Journal of Bone and Mineral Metabolism

Year:

2011

Language:

english

File:

PDF, 596 KB

english, 2011

20

Localization and inhibitory effect of basic fibroblast growth factor on chondrogenesis in cultured mouse mandibular condyle

Takuya Ogawa, Hitoyata Shimokawa, Kenji Fukada, Shoichi Suzuki, Shunichi Shibata, Keiichi Ohya, Takayuki Kuroda

Journal:

Journal of Bone and Mineral Metabolism

Year:

2003

Language:

english

File:

PDF, 361 KB

english, 2003

21

Combination of 3D tissue engineered scaffold and non-viral gene carrier enhance in vitro DNA expression of mesenchymal stem cells

Hossein Hosseinkhani, Tony Azzam, Hisatoshi Kobayashi, Yosuke Hiraoka, Hitoyata Shimokawa, Abraham J. Domb, Yasuhiko Tabata

Journal:

Year:

2006

Language:

english

File:

PDF, 374 KB

english, 2006

22

Gravity stress elevates the nociceptive threshold level with immunohistochemical changes in the rat brain

Yasuhiro Kumei, Reiko Shimokawa, Mari Kimoto, Yasuko Kawauchi, Hitoyata Shimokawa, Koshi Makita, Keiichi Ohya, Kazuo Toda

Journal:

Acta Astronautica

Year:

2001

Language:

english

File:

PDF, 1.77 MB

english, 2001

23

Space Flight and Insulin-like Growth Factor-I Signaling in Rat Osteoblasts

YASUHIRO KUMEI, HIROSHI NAKAMURA, SADAO MORITA, HIDEO AKIYAMA, MASAHIKO HIRANO, KEI'ICHI OHYA, KEN'ICHI SHINOMIYA, HITOYATA SHIMOKAWA

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 1.58 MB

2002

24

Coinduction of GTP Cyclohydrolase I and Inducible NO Synthase in Rat Osteoblasts during Space Flight : Apoptotic and Self-protective Response?

YASUHIRO KUMEI, SADAO MORITA, HIROSHI NAKAMURA, HIDEO AKIYAMA, MASAHIKO HIRANO, HITOYATA SHIMOKAWA, KEI'ICHI OHYA

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 2.24 MB

2003

25

Antagonism between Apoptotic (Bax/Bcl-2) and Anti-Apoptotic (IAP) Signals in Human Osteoblastic Cells under Vector-Averaged Gravity Condition

HIROSHI NAKAMURA, YASUHIRO KUMEI, SADAO MORITA, HITOYATA SHIMOKAWA, KEIICHI OHYA, KENICHI SHINOMIYA

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 2.05 MB

2003

26

Hypergravity Stimulates Osteoblast Phenotype Expression: A Therapeutic Hint for Disuse Bone Atrophy

SADAO MORITA, HIROSHI NAKAMURA, YASUHIRO KUMEI, HITOYATA SHIMOKAWA, KEIICHI OHYA, KENICHI SHINOMIYA

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 24 KB

english, 2004

27

Osteoblast Responsiveness to 1α,25-Dihydroxyvitamin D3 during Spaceflight

YASUHIRO KUMEI, SADAO MORITA, HIROSHI NAKAMURA, HISAKO KATANO, KEI'ICHI OHYA, HITOYATA SHIMOKAWA, CLARENCE F. SAMS, PEGGY A. WHITSON

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 41 KB

english, 2004

28

Platelet-Activating Factor Receptor Signals in Rat Osteoblasts during Spaceflight

YASUHIRO KUMEI, SADAO MORITA, HIROSHI NAKAMURA, HIDEO AKIYAMA, HISAKO KATANO, HITOYATA SHIMOKAWA, KEI'ICHI OHYA

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 55 KB

english, 2004

29

Microgravity Signal Ensnarls Cell Adhesion, Cytoskeleton, and Matrix Proteins of Rat Osteoblasts : Osteopontin, CD44, Osteonectin, and α-Tubulin

YASUHIRO KUMEI, SADAO MORITA, HISAKO KATANO, HIDEO AKIYAMA, MASAHIKO HIRANO, KEI'ICHI OYHA, HITOYATA SHIMOKAWA

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

30

Small GTPase Ras and Rho Expression in Rat Osteoblasts during Spaceflight

YASUHIRO KUMEI, HITOYATA SHIMOKAWA, KEI'ICHI OHYA, HISAKO KATANO, HIDEO AKIYAMA, MASAHIKO HIRANO, SADAO MORITA

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

31

LPS-Induced Inhibition of Osteogenesis Is TNF-α Dependent in a Murine Tooth Extraction Model

Nobuyoshi Tomomatsu, Kazuhiro Aoki, Neil Alles, Niroshani S Soysa, Anower Hussain, Hiroyuki Nakachi, Souma Kita, Hitoyata Shimokawa, Keiichi Ohya, Teruo Amagasa

Journal:

Journal of Bone and Mineral Research

Year:

2009

Language:

english

File:

PDF, 1.85 MB

english, 2009

32

The pivotal role of the alternative NF-κB pathway in maintenance of basal bone homeostasis and osteoclastogenesis

Niroshani S Soysa, Neil Alles, Debra Weih, Agnes Lovas, Anower Hussain Mian, Hitoyata Shimokawa, Hisataka Yasuda, Falk Weih, Eijiro Jimi, Keiichi Ohya, Kazuhiro Aoki

Journal:

Journal of Bone and Mineral Research

Year:

2010

Language:

english

File:

PDF, 591 KB

english, 2010

33

Expression of PDGF-β receptor, EGF receptor, and receptor adaptor protein Shc in rat osteoblasts during spaceflight

Hideo Akiyama, Shozo Kanai, Masahiko Hirano, Hitoyata Shimokawa, Hisako Katano, Chiaki Mukai, Shunji Nagaoka, Sadao Morita, Yasuhiro Kumei

Journal:

Molecular and Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 176 KB

english, 1999

34

In situ hybridization for matrix metalloproteinase-1 and cathepsin K in rat root-resorbing tissue induced by tooth movement

Sayaka Domon, Hitoyata Shimokawa, Yoshiro Matsumoto, Satoshi Yamaguchi, Kunimichi Soma

Journal:

Archives of Oral Biology

Year:

1999

Language:

english

File:

PDF, 239 KB

english, 1999

35

Disturbance of Electrolyte Balance in Vitreous of Chicks With Form-Deprivation Myopia

Yuko Seko, Hitoyata Shimokawa, Jijing Pang, Takashi Tokoro

Journal:

Japanese Journal of Ophthalmology

Year:

2000

Language:

english

File:

PDF, 53 KB

english, 2000

36

Identification of the cell type origin of odontoma-like cell masses in microphthalmic (mi/mi) mice by in situ hybridization

Yuko Nakajima, Hitoyata Shimokawa, Kunihiro Terai, Hitoshi Onoue, Yoshiki Seino, Hiroyuki Tanaka, Shizuo Sobue, Yukihiko Kitamura, Shintaro Nomura

Journal:

Pathology International

Year:

1996

Language:

english

File:

PDF, 2.64 MB

english, 1996

37

Basic Fibroblast Growth Factor Induces Apoptosis in Myofibroblastic Cells Isolated from Rat Palatal Mucosa

Noriko Funato, Keiji Moriyama, Hitoyata Shimokawa, Takayuki Kuroda

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 841 KB

english, 1997

38

Transforming Growth Factor-β1 Modulates Myofibroblastic Phenotype of Rat Palatal Fibroblastsin Vitro

Masahiko Yokozeki, Keiji Moriyama, Hitoyata Shimokawa, Takayuki Kuroda

Journal:

Experimental Cell Research

Year:

1997

Language:

english

File:

PDF, 729 KB

english, 1997

39

In Vivo and In Vitro Association of Retinoic Acid with Form-deprivation Myopia in the Chick

YUKO SEKO, HITOYATA SHIMOKAWA, TAKASHI TOKORO

Journal:

Experimental Eye Research

Year:

1996

Language:

english

File:

PDF, 379 KB

english, 1996

40

Effects of non-collagenous proteins on the formation of apatite in calcium β-glycerophosphate solutions

Yutaka Doi, Takashi Horiguchi, Seug-Hyo Kim, Yutaka Moriwaki, Nobukazu Wakamatsu, Masanori Adachi, Kyomi Ibaraki, Keiji Moriyama, Satoshi Sasaki, Hitoyata Shimokawa

Journal:

Archives of Oral Biology

Year:

1992

Language:

english

File:

PDF, 2.00 MB

english, 1992

41

Identification of the leucine-rich amelogenin peptide (LRAP) as the translation product of an alternatively spliced transcript

Carolyn W. Gibson, Ellis Golub, Wendi Ding, Hitoyata Shimokawa, Marian Young, John Termine, Joel Rosenbloom

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 724 KB

english, 1991

42

Smad3 is required for enamel biomineralization

Masahiko Yokozeki, Elaine Afanador, Masumi Nishi, Kazuyuki Kaneko, Hitoyata Shimokawa, Koutaro Yokote, Chuxia Deng, Kunihiro Tsuchida, Hiromu Sugino, Keiji Moriyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 438 KB

english, 2003

43

Interferon-γ inhibits the myofibroblastic phenotype of rat palatal fibroblasts induced by transforming growth factor-β1 in vitro

Masahiko Yokozeki, Yoshiyuki Baba, Hitoyata Shimokawa, Keiji Moriyama, Takayuki Kuroda

Journal:

Year:

1999

Language:

english

File:

PDF, 202 KB

english, 1999

44

Immunochemical and biochemical characteristics of enamel proteins in hypocalcified amelogenesis imperfecta

Yuzo Takagi, Haruko Fujita, Hisako Katano, Hitoyata Shimokawa, Takayuki Kuroda

Journal:

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Year:

1998

Language:

english

File:

PDF, 7.40 MB

english, 1998

45

Collagen crosslinks: Direct quantitative determination of stable structural crosslinks in bone and dentin collagens

Gerald L. Mechanic, Yoshinori Kuboki, Hitoyata Shimokawa, Kumiko Nakamoto, Satoshi Sasaki, Yasuhiro Kawanishi

Journal:

Biochemical and Biophysical Research Communications

Year:

1974

Language:

english

File:

PDF, 521 KB

english, 1974

46

Microgravity induces prostaglandin E2 and interleukin-6 production in normal rat osteoblasts: role in bone demineralization

Yasuhiro Kumei, Hitoyata Shimokawa, Hisako Katano, Eiji Hara, Hideo Akiyama, Masahiko Hirano, Chiaki Mukai, Shunji Nagaoka, Peggy A. Whitson, clarence F. Sams

Journal:

Journal of Biotechnology

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

47

An improved quantitative RT-PCR fluorescent method for analysis of gene transcripts in the STS-65 space shuttle experiment

Hideo Akiyama, Shozo Kanai, Masahiko Hirano, Yasuhiro Kumei, Hitoyata shimokawa, Hisako Katano, Eiji Hara, Shuolin Song, Chiaki Mukai, Shunji Nagaoka

Journal:

Journal of Biotechnology

Year:

1996

Language:

english

File:

PDF, 813 KB

english, 1996

48

Homeobox Gene Expression during Bone Formation Induced by BMP

Tadahiro Iimura, Otto Baba, Yutaka Maruoka, Kohsuke Takeda, Satoshi Sasaki, Hitoyata Shimokawa, Shinichiro Oida

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 423 KB

english, 1996

49

Impregnation of Plasmid DNA into Three-Dimensional Scaffolds and Medium Perfusion Enhance in Vitro DNA Expression of Mesenchymal Stem Cells

Hosseinkhani, Hossein, Inatsugu, Yasuyuki, Hiraoka, Yosuke, Inoue, Sachiko, Shimokawa, Hitoyata, Tabata, Yasuhiko

Journal:

Tissue Engineering

Year:

2005

Language:

english

File:

PDF, 331 KB

english, 2005

50

Effects of Growth Factors on Mucosal Scar Fibroblasts in Culture â a Possible Role of Growth Factors in Scar Formation

Moriyama, Keiji, Shimokawa, Hitoyata, Susami, Takafumi, Sasaki, Satoshi, Kuroda, Takayuki

Journal:

Matrix - Collagen and Related Research

Year:

1991

Language:

english

File:

PDF, 1016 KB

english, 1991

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